Ischemia: Inadequate blood supply (circulation) to a local area due to blockage of the blood vessels to the area. Ischemia is the lack of delivery of oxygen to a major organ, most often affecting the heart or the brain. Ischemia occurs when your blood cannot flow through your arteries as well as it should, and your intestines do not receive the necessary oxygen to perform normally. Ischemia occurs when living tissue is deprived of oxygen. Ischemia causes rapid damage to tissue of all types, though some tissues are more sensitive than others. Ischemia in the brain causes stroke, while ischemia in the heart leads to a heart attack (also known as a myocardial infarction). However, ischemia may first present when an artery becomes so completely blocked so that blood cannot get to the brain or lungs. In very rare cases, blood clots can form in the legs during long airplane flights, causing almost immediate ischemia. When your heart suffers from ischemia, you will typically experience pain or discomfort in your chest.

Glutathione diminishes damage to oxygen-deprived tissue during ischemia.



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